Antioxidant, Anti-Inflammatory Activities, and Neuroprotective Behaviors of Phyllanthus emblica L. Fruit Extracts

Phyllanthus emblica L. is traditionally used as both medicine and food in Taiwan. In this study, we evaluated the antioxidant, anti-inflammatory, neuroprotection bioactivities of P. fruit. fruit extracts had a high content total phenol flavonoids, chlorogenic acids. For antioxidant capacity, 95% ethanol-extracted best DPPH radical scavenging activity, ferrous ion chelating ability, reducing power compared with hot water, 50% ethanol, commercial extracts, showed highest lipid peroxidation inhibition. The present results have demonstrated that can protect oxidative degradation lipids by inhibiting FeCl3-ascorbate-mediated peroxidation. anti-inflammatory dose-dependent inhibition nitric oxide lipopolysaccharide-stimulated RAW264.7 cells significantly COX-2 bioactivity, higher percentages pheochromocytoma cell protection than extracts. Hot water ethanol PC12 hydroalcoholic neuroprotective effect against damage, which could be due to their activity. daily health beverages, foods, cosmetic products.